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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Serine and Leptin

supplement:

Serine

drug:

Leptin

Research Papers that Mention the Interaction

Leptin induced tyrosine and serine phosphorylation of STAT1 and STAT3, both of which were suppressed by AG490, and serine phosphorylation was also suppressed by SB202190.
Endocrinology  •  2008  |  View Paper
Acute leptin exposure increased eNOS serine 1177 phosphorylation and caused Erk activation.
Journal of Investigative Medicine  •  2007  |  View Paper
Interestingly, leptin in the NAcc core significantly blocks the increase of GluA1 phosphorylation levels at serine 845 induced by acute administration of cocaine.
Neuroreport  •  2018  |  View Paper
Thus, suppressor of cytokine signaling-3 (SOCS3) can physically block the leptin …, C-Jun Nterminal kinase, and protein kinase Ccan catalyze the inhibitory serine … leptin and insulin signaling systems in the hypothalamus and can also induce the … and inactivate proteins of the leptin and insulin signaling cascade (11, 12).
Endocrinology  •  2012  |  View Paper
Moreover, the administration of 0.5% l-serine decreased the concentrations of leptin , malondialdehyde, interleukin-1β, and interleukin-6, while it increased those of superoxide dismutase and glutathione, in both the serum and hypothalamus.
Front. Endocrinol.  •  2018  |  View Paper