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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“ Leptin induced tyrosine and serine phosphorylation of STAT1 and STAT3, both of which were suppressed by AG490, and serine phosphorylation was also suppressed by SB202190.”
Leptin enhances human beta-defensin-2 production in human keratinocytes.“Acute leptin exposure increased eNOS serine 1177 phosphorylation and caused Erk activation.”
“Interestingly, leptin in the NAcc core significantly blocks the increase of GluA1 phosphorylation levels at serine 845 induced by acute administration of cocaine.”
Leptin in the nucleus accumbens blocks the increase of GluA1 phosphorylation induced by acute cocaine administration“Thus, suppressor of cytokine signaling-3 (SOCS3) can physically block the leptin …, C-Jun Nterminal kinase, and protein kinase Ccan catalyze the inhibitory serine … leptin and insulin signaling systems in the hypothalamus and can also induce the … and inactivate proteins of the leptin and insulin signaling cascade (11, 12).”
“Moreover, the administration of 0.5% l-serine decreased the concentrations of leptin , malondialdehyde, interleukin-1β, and interleukin-6, while it increased those of superoxide dismutase and glutathione, in both the serum and hypothalamus.”
Long-Term l-Serine Administration Reduces Food Intake and Improves Oxidative Stress and Sirt1/NFκB Signaling in the Hypothalamus of Aging Mice
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