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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Serine
supplement:
Glutamic Acid
Research Papers that Mention the Interaction
“ConclusionsA combination of serine and glutamic acid residues in the chelator sequence confers increased renal excretion and relatively low renal uptake of 99mTc-labelled Affibody molecules.”
Development and preclinical characterisation of 99mTc-labelled Affibody molecules with reduced renal uptake“Substitution by Ser gave further 3-8-fold reductions in affinity, whereas the largest decreases, >10(5)-fold, were observed for mutations to Arg and Glu.”
“It was proposed that interactions between the side chains of Ser 8 and Glu 11 are important in determining the pH dependence of the helix content.”
“257, 9582-9587); its reactivity toward L-glutamic acid was strongly inhibited by L-serine , but not by 2-(methyl-amino)isobutyric acid; and 3) a Na+-independent system similar to System XC- described in fetal human lung fibroblasts (Bannai, S., and Kitamura, E. (1980) J. Biol.”
“The apparent digestibility of alanine (P = 0.05), aspartic acid (P = 0.07), glutamic acid (P = 0.02), glycine (P = 0.05), proline (P = 0.02), and serine (P = 0.04) responded quadratically to CP content increase.”
Dietary protein reduction on microbial protein, amino acid digestibility, and body retention in beef cattle: 2. Amino acid intestinal absorption and their efficiency for whole-body deposition.“Indeed, a phosphomimetic serine‐glutamic acid mutation reduced translocation of PKC Apl II while blocking phosphorylation with a serine‐alanine mutation enhanced translocation and led to the persistence of the kinase at the membrane longer after the end of the stimulation.”
“Efflux profiles with 2‐min temporal resolution in response to 24‐min OGD show that efflux of D‐ser slightly precedes efflux of L‐glu by one 2‐min sampling interval.”
“Together with information inferred from a human carboxylesterase crystal structure, it was concluded that this serine provides an important structural support for the spatial orientation of the glutamic acid , stabilizing the catalytic triad so that it can perform the hydrolysis.”
“Amino acids that did not stimulate usually had no effect in mixtures with a stimulating compound, but glutamic acid reduced the response to serine in the medial sensillum.”
“Substitution of glutamic acid for serine at positions 26, 34, and 90 reduced protein helical contents by 10, 6, and 14%, respectively.”
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