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“Amino acid auxotrophs, including serine , threonine, glutamine, and tryptophan auxotrophs, exhibit strongly decreased tolerance to gentamicin , which cannot be restored by supplying the corresponding amino acids to the culture.”
“violaces 1935 in the synthetic medium the level of gentamicin biosynthesis increased on the average by 2--2.5 times when cyancobalamine, methylcobalamine, L-methionine or L-serine were added to the medium.”