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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Serine
drug:
Gabapentin
Research Papers that Mention the Interaction
“In contrast l-Serine (100 μg, ICV) failed to block the antinociceptive action of gabapentin.”
The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed byd-serine“When compared to saline-treated rats, animals pretreated with 100 mg/kg gabapentin showed suppression of the acetic acid–induced increases in glutamate, aspartate, and serine concentrations.”
“The effects of intraperitoneally administered gabapentin and 3‐isobutyl‐gamma aminobutyric acid were reversed by intrathecal pretreatment with D‐serine (100 micro gram) but not by L‐serine.”
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