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Last Updated: 3 years ago

Possible Interaction: Selenomethionine and Irinotecan

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supplement:

Selenomethionine

drug:

Irinotecan

Research Papers that Mention the Interaction

“CONCLUSIONS: Selenomethionine at 2,200 mug/d did not allow the safe escalation of irinotecan beyond the previously defined MTD of 125 mg/m(2).”

A phase I and pharmacokinetic study of fixed-dose selenomethionine and irinotecan in solid tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2006 | View Paper

“Results from this laboratory have demonstrated that MSC and SLM are highly effective modulators of irinotecan cure rates in de novo sensitive and resistant human tumor xenografts.”

Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.

Clinical colorectal cancer • 2005 | View Paper

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