Possible Interaction: Selenium and Vitamin C

“ VCE prevents the smoke and X-ray-induced selenium , zinc, magnesium, and copper decrease to strengthen the antioxidant trace element levels in the serum of the technicians.”

“These results suggest that supplemental ascorbic acid may have a beneficial effect on the bioavailability of the natural Se in foods.”

“Moreover, synergistic interactions with selenium and ascorbic acid have been reported.”

“Therefore, there are selenium antagonistic elements that inhibit the anticarcinogenic effects of selenium and other antioxidant micronutrients such as ascorbic acid , retinol, beta-carotene, alpha-tocopherol, and some other elements have a synergistic effect on the prevention of cancer.”

“Addition of ascorbic acid and selenium to the medium increased follicular survival (from 29% to 86%) and resulted in the development of healthy preovulatory follicles (> 400 microm) producing estradiol.”

“The bioaccessibility of Se significantly increased in response to vitamin C (VC), vitamin E (VE), vitamin B6 (VB6) and vitamin B9 (VB9), especially VC, which also increased the bioaccessibility of Zn and decreased that of Cd.”

“Total amino acid and vitamin C contents were significantly enhanced by the application of selenium.”

“MAIN CONCLUSIONS: Lower vitamin C and selenium in Indians, particularly in combination, could play a part in their increased risk of CHD.”

“Using data from the same studies, we calculated that vitamin C (1-6 g/day) decreased the duration of the cold episodes by 0.93 +/- 0.22 ( SE ) days; the relative decrease in the episode duration was 21%.”

“There was a significant interaction between selenium and ascorbic acid levels which could not be explained by cigarette use.”