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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Selenium
supplement:
Vitamin B 12
Research Papers that Mention the Interaction
“For Se and cobalamin, the daily intake of our patients (Se 48 ± 16 µg/day; cobalamin 3.5 µg/day) was slightly higher than the recommended daily averages (RDAs) (40 µg/day and 1.8 µg/day, respectively).”
The monitoring of trace elements in blood samples from patients with inborn errors of metabolism“CONCLUSIONS: Injecting ewes from a Se-deficient flock 4 weeks prior to mating with 48 or 60 mg Se and 12 or 15 mg vitamin B12 increased and maintained the Se status of ewes for at least 300 days, and of their lambs from birth to weaning.”
Dose-response effects of long-acting injectable vitamin B12 plus selenium (Se) on the vitamin B12 and Se status of ewes and their lambs“A significant (P < 0.05) interaction of vitamin B12 and selenium was found on growth of rats fed vitamin B12 deficient or control diets.”
“Rats pair-fed 9 mg/kg selenium with vitamin B12 had significantly lower liver and kidney selenium levels and significantly higher blood selenium levels compared to rats fed the diet without vitamin B12.”
“These results show that vitamin B12 deficiency significantly decreases the ability of rats to methylate selenium.”
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