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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Selenium
drug:
Triiodothyronine
Research Papers that Mention the Interaction
“ T3 synthesis correlates closely with the selenium levels.”
[Effect of selenium administration on various laboratory parameters of patients at risk for sepsis syndrome].“Meta-analysis results showed that the serum free triiodothyronine (FT3) levels in patients was greatly reduced after selenium supplementation compared to placebo treatment (MD =-0.40; 95% confidential interval (CI): -0.70--0.10; Z=2.61; P=0.009).”
“The correlation between Se and T3 , along with the parallel decrease in T4 deiodination, indicates that reduced deiodination might be related to the transient decrease in serum Se.”
“Serum 3,3',5-triiodothyronine T3 ) decreased in the high selenium group , increased in the low selenium group, and was significantly different between groups from d 45 onward.”
“Although the disease process per se may explain the lower plasma T3 concentrations, it is also possible, inasmuch as these patients were in early-stage breast cancer, that selenium status may be influencing T3 levels via changes in the activity of the selenoenzyme type 1 iodothyronine deiodinase.”
“ T3 treatment resulted in a rise of serum TT3 from a baseline of 137 +/- 16 (+/- SE ) to a peak of 239 +/- 15 ng/dl.”
“Furthermore, selenium had significant effects on the concentration of T4 and T3 (P < 0.05).”
Effects of Dietary Supplementation with Selenium and Vitamin E on Growth Performance, Nutrient Apparent Digestibility and Blood Parameters in Female Sika Deer (Cervus nippon)“We found … selenium Se ) supplementation increased … levels of triiodothyronine (25%, p b 0.001) and thyroxine (18%, p b 0.05) and promoted a tryptophan hydroxylase 2 (TPH 2) … decrease (17%, p b 0.01) and tyrosine hydroxylase (TH) expression increase (202%, p b 0.01) in the hippocampus.”
“On the …, selenium supplementation resulted in significant increases in libido (P < 0.001), mean values of ejaculate volume (P < 0.001), percentage of forward motility (P = …), total functional sperm fraction (P < 0.001), semen initial fructose concentration (P = 0.031), and blood serum concentrations of both testosterone and triiodothyronine (…).”
“Supplementation of calves with intraruminal Se pellets increased the basal plasma concentration of 3,5,3'-triiodothyronine and reduced the basal plasma concentration of thyroxine for both herds.”
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