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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Selenium
drug:
Topiramate
Research Papers that Mention the Interaction
“ SE was controlled in 68.6% of patients receiving TPM either as the last drug (20) or not (15), and in 14 of the 20 patients receiving TPM as the last drug (70%).”
Topiramate in the Treatment of Generalized Convulsive Status Epilepticus in Adults: A Systematic Review with Individual Patient Data Analysis“ Topiramate was successful in terminating SE in five (25%) patients; possibly successful in 11 (55%); and not successful in four (20%).”
“Compared to placebo, there … weight loss with topiramate in all analyses: 9.5 kg (SE 1.… complete case analysis (N = 86), 6.8 kg ( SE 0.66) using LOCF (N = 561), 6.4 kg (SE 0.90) … = 561) and 1.5 kg (SE 0.28) using BOCF (N = 561).”
“Cytosolic Ca2+ release and lipid peroxidation levels were higher in H2O2 group than in control, Se and TPM combination groups although their levels were decreased by incubation of Se and TPM combination.”
Effects of Selenium and Topiramate on Cytosolic Ca2+ Influx and Oxidative Stress in Neuronal PC12 Cells
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