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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Tamoxifen treatment lowered levels of serum cholesterol by (mean +/- SE ) 12 +/- 2%, low density lipoprotein cholesterol by 19 +/- 3%, and fibrinogen by 18 +/- 4% (P < 0.0001 vs. placebo for each).”
The effect of the anti-estrogen tamoxifen on cardiovascular risk factors in normal postmenopausal women.“ Organic selenium may provide added benefit when combined with tamoxifen in adjuvant therapy or prevention.”
“These results indicate that the growth inhibition synergy and reversal of tamoxifen resistance by combination of selenium with tamoxifen occurs via a tamoxifen-induced cell cycle arrest, allowing more cells to enter the intrinsic apoptotic pathway elicited by selenium. [”
“However, tamoxifen reduced uptake [50% inhibitory dose, 8.6 +/- 0.9 ( SE ) microM] and competed for Ca2+ channel antagonist binding sites labeled by [3H]-(+)PN200-110 (ki = 2.2 +/- 0.3 microM).”
Calcium channel antagonist properties of the antineoplastic antiestrogen tamoxifen in the PC12 neurosecretory cell line.
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