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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Selenium
supplement:
Sodium Selenite
Research Papers that Mention the Interaction
“This study shows that … micrograms/d of sodium selenite for 8 wk, … 10(-7) M Se (as sodium selenite), result in a significant augmentation of the ability of peripheral blood lymphocytes to respond … phytohemagglutinin or alloantigen (mixed lymphocyte reaction) and to express high affinity Il2-R on their surface.”
Supplementation with selenium and human immune cell functions: I. Effect on lymphocyte proliferation and interleukin 2 receptor expression“The sodium selenite resulted in significant rise of blood selenium levels and concurrent increase in erythrocytic glutathione peroxidase (GPx) activity.”
Effect of sub-chronic selenium toxicosis on lipid peroxidation, glutathione redox cycle and antioxidant enzymes in calves.“In addition, this study examined the supplementation of Se at 4‐ppm levels in the form of sodium selenite either before initiation or during initiation and/or promotion phase's increases lymphocyte Se concentrations.”
“A diet containing sodium selenite and fulvic acid caused the selenium concentrations in the organs, with the exception of the spleen, to be lower than observed with the selenite-only diet.”
“Feeding mice a diet supplemented with sodium selenite increased the selenium concentration in the kidney, liver, spleen, lung, heart and blood.”
“Oral Se supplementation with 180 µg/day or 240 µg/day (selenomethionine) and 200 µg/day ( Sodium Selenite ), significantly decreased lipid hydroperoxide levels and increased GPx in plasma, erythrocyte, and muscle.”
“Different responses of Se biomarkers after supplementation with selenomethionine and sodium selenite have been observed and some of them could be due to genetic polymorphisms, mainly single nucleotide polymorphisms (SNPs).”
“Protection by selenium supplementation with either sodium selenite (SS, 30 nM) or selenomethionine (SM, 10 microM) was also investigated.”
“Upon Se supplementation as sodium selenite at various concentrations in the growth medium, a continuous increase in glutathione peroxidase (GSH-Px) activity and Se content was observed.”
“Ingestion of sodium selenite 400 micrograms/day (182.8 micrograms pure selenium) resulted in a significant increase in plasma selenium levels.”
“As compared with … and 2, SS and SSC … increased Se concentration, glutathione peroxidase (GPx) and thioredoxin reductase (TR) activities, total antioxidant capacity, and the mRNA levels of GPx-1, GPx-…, TR-1, and TR-3 (P < 0.05) and decreased drip loss and malondialdehyde (MDA) content (P < 0.05).”
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