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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Selenium and Multivitamin Preparation

supplement:

Selenium

Research Papers that Mention the Interaction

Multivitamin use, for example, declined from 37% to 31%, and rates of vitamin C, vitamin E, and selenium use decreased, perhaps in response to research findings showing no benefit.
JAMA  •  2016  |  View Paper
We found positive significant correlations between use of vitamin supplements with both α-tocopherol (β = 0.096; SE = 0.05; P = 0.045) and threonate normalized levels (β = 0.19; SE = 0.06; P = 0.001).
American journal of respiratory and critical care medicine  •  2015  |  View Paper
Multivitamins … selenium in a single supplement, vs placebo, also reduced the risk of secondary events of combined outcomes for disease progression (CD4 cell count ≤250/μL, … HR, 0.56; 95% CI, 0.33-0.95; P = .03; AER, 6.48/100 person-years; censoring rate, 0.90; 23 events]).
multivitamins … selenium had a significantly lower risk vs placebo of reaching CD4 cell count 250/μL or less (adjusted hazard ratio [HR], 0.46; 95% CI, ….79/100 person-years; censoring rate, 0.92; 17 events; placebo AER, 9.22/100 person-years; censoring rate, 0.85; 32 events).
JAMA  •  2013  |  View Paper
The miRNA changes that accompany SE are predicted to impact levels of multiple proteins involved in neuronal morphology and function, gliosis, neuroinflammation, and cell death.
Front. Mol. Neurosci.  •  2013  |  View Paper