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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Selenium
drug:
Irinotecan
Research Papers that Mention the Interaction
“In vivo experiment showed Nano Se at a dose of 4 mg/kg/day significantly alleviated adverse effects induced by irinotecan (60 mg/kg) treatment.”
“The combination of Nano Se and irinotecan dramatically inhibited tumor growth and significantly induced apoptosis of tumor cells in HCT-8 cells xenografted tumor.”
“The combination of Nano Se and irinotecan showed increased cytotoxic effect with HCT-8 tumor cells likely by p53 mediated apoptosis.”
Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles.“The MSC-dependent increase in Se level in normal tissues may contribute to the protective effect against irinotecan toxicity observed in those tissues.”
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