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Journal of cardiopulmonary rehabilitation • 2005 | View Paper
“The ratio of reduced to oxidised glutathione and the total antioxidant capacity were significantly reduced in selenium exposed organisms compared to control organisms.”
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP • 2005 | View Paper
“ Selenium caused a dose-dependent improvement in cardiac performance and attenuated the decrease in the ratio of reduced glutathione to oxidized glutathione , as well as the increased level of malondialdehyde in I/R heart.”
Antioxidants & redox signaling • 2005 | View Paper
“Biochemical analyses of H-4 cells demonstrated that selenium treatment caused a significant dose-dependent increase in oxidized and reduced glutathione ( GSSG and GSH) as well as in the GSSG:GSH ratio as was previously observed in liver in vivo.”
“These results indicate that selenium affects all "synthetic" stages of the cell cycle, and elevated GSSG or the GSSG :GSH ratio may explain the antiproliferative effects of selenium on cells.”
“High Se significantly increased the concentrations of hepatic nonprotein sulfhydryls (NPSH) and oxidized glutathione (GSSG) as well as the GSSG:NPSH ratio.”