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Last Updated: 3 years ago

Possible Interaction: Selenium and Glutathione Disulfide

Research Papers that Mention the Interaction

The GSH GSSG ratio levels significantly dropped from baseline 462.12 to 276.40 postexercise (pooled SE = 5.98).
Journal of cardiopulmonary rehabilitation  •  2005  |  View Paper
The ratio of reduced to oxidised glutathione and the total antioxidant capacity were significantly reduced in selenium exposed organisms compared to control organisms.
Aquatic toxicology  •  2012  |  View Paper
Selenium yeast-fed groups maintained higher levels of GSSG before and after HS with a resultant lower GSH/GSSG ratio.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP  •  2005  |  View Paper
Selenium caused a dose-dependent improvement in cardiac performance and attenuated the decrease in the ratio of reduced glutathione to oxidized glutathione , as well as the increased level of malondialdehyde in I/R heart.
Antioxidants & redox signaling  •  2005  |  View Paper
Biochemical analyses of H-4 cells demonstrated that selenium treatment caused a significant dose-dependent increase in oxidized and reduced glutathione ( GSSG and GSH) as well as in the GSSG:GSH ratio as was previously observed in liver in vivo.
These results indicate that selenium affects all "synthetic" stages of the cell cycle, and elevated GSSG or the GSSG :GSH ratio may explain the antiproliferative effects of selenium on cells.
Cancer research  •  1985  |  View Paper
High Se significantly increased the concentrations of hepatic nonprotein sulfhydryls (NPSH) and oxidized glutathione (GSSG) as well as the GSSG:NPSH ratio.
The Journal of nutrition  •  1983  |  View Paper