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Last Updated: 3 years ago
supplement:
Selenium
Research Papers that Mention the Interaction
“But DOX-Se/MBG nanospheres reduced the acute cytotoxicity to MG63 because of the co-operative effect of Se and DOX.”
Design and evaluation a kind of functional biomaterial for bone tissue engineering: Selenium/mesoporous bioactive glass nanospheres.“ Se han utilizado doxorrubicina , ifosfamida, carboplatino y etopósido, entre otros.”
“It is found that both drugs were able to inhibit cell proliferation in a dose-dependent way and the combined treatment with ADM and Se NPs was more effective in inhibiting cell growth than each of the two drugs alone.”
“By combining doxorubicin with selenium , we were successful in producing a brisk enhancement of apoptosis.”
“ Selenium reduced the abundance of phospho-GSK3β induced by doxorubicin , whereas chemical inhibition of GSK3β activity muted the apoptotic response to the selenium/doxorubicin combination.”
“Several lines of evidence converged to support the notion that this effect is important in mediating the synergy between selenium and doxorubicin.”
“ Selenium treatment of the doxorubicin-resistant cell line , U-1285dox, derived from human small cell carcinoma of the lung, resulted in massive apoptosis.”
“Addition of chemotherapeutic agents either Taxol or Doxorubicin with Selenium caused further inhibition of MCF-7, SKBR-3, RH2, HCF8, and HepG2 cells.”
“However, addition of Adriamycin or Taxol in combination with Selenium caused small but significant inhibition of prostate cancer cells LNCap and PC-3.”
“Supplementation of Selenium enhanced chemotherapeutic effect of Taxol and Doxorubicin in these cells beyond that seen with the chemotherapeutic drugs used alone.”
“We suggest to supplement these patients with vitamins A and E, and selenium to reduce the side effects of ADR.”
“Liver histopathology was assessed to determine the dose at which Se may best inhibit Dox induced liver toxicity.”
“We investigated the mechanism of DOX hepatotoxicity and the protective effect of different doses of Se on Dox induced liver damage.”
Use of selenium to ameliorate doxorubicin induced hepatotoxicity by targeting pro-inflammatory cytokines“Some individual doses of Se or TA induced a significant toxicity in SCs, however, when combined with DOX , there was a decrease in cell death, LDH extracellular activity, number of apoptotic cells and caspase-3 activity.”
“The co-administration of DOX with Se increased OCR, significantly prevented O2- overproduction, and decreased LPO.”
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