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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Combination therapy of DTX and Se could be used as an effective strategy for protection of kidney cells against adverse effects of DTX.”
Selenium attenuates docetaxel-induced apoptosis and mitochondrial oxidative stress in kidney cells“Cell number and viability, and the levels of apoptosis, JC1, ROS, and [Ca2+]i, induced by DTX , were further increased following addition of Se.”
“Therefore, combination therapy with Se and DTX may represent an effective strategy for the treatment of glioblastoma cells and may be associated with TRPM2-mediated increases in oxidative stress and [Ca2+]i.”
“Conclusion Our in vitro study indicated that the combination of selenium with docetaxel inhibits cell proliferation through apoptosis and cell arrest in the G2/M phase in MDA-MB-231 breast cancer cells.”
“Results In the … group docetaxel … selenium at 10µM) showed a significantly decreased percentage of cell growth (15% vs. 28%; P = 0.004), a significantly increased percentage of late …), and an increased cell cycle arrest in the G2/M phase (P = 0.001) compared with the solitary docetaxel therapy group.”
Effects of combination therapy of docetaxel with selenium on the human breast cancer cell lines MDA-MB-231 and MCF-7
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