Possible Interaction: Selenium and Calcium Supplement

“ Se han realizado diversas investigaciones que demuestran el beneficio … supone la suplementación con leche enriquecida en calcio y vitamina D en grupos vulnerables como los adultos mayores y las mujeres posmenopáusicas, en los que mejora sustancialmente el recambio óseo y aumenta la densidad y la fuerza de los huesos.”

“Both … Ca … Se and Zn: a difference of 1 g kg-1 in soil Fe changed soil Se by 2.820 μg kg-1 and soil …-1 in soil Ca changed soil Se by 3.249 μg kg-1 and soil Zn by 0.356 mg kg-1, respectively.”

“Both the calcium infusions decreased serum PTH-(1-84) levels from a mean of 23.2 +/- 2.0 (+/- SE ) to 6.4 +/- 1.0 and 5.6 +/- 1.0 ng/L for the rapid and slow infusions, respectively, with no obvious rate dependence.”

“Significant correlations between Se and K, Fe, Ca , Mg, and Zn were noticed.”

“ Ca was found to be correlated negatively with Cu and positively with Se.”

“The rations high in fermentable carbohydrates, nitrates, sulfates, calcium or hydrogen cyanide negatively influence the organism’s use of the selenium contained in the diet.”

“The beneficial influence of coadministration of selenium in case of calcium lets us suggest that an issue of its possible use as an adjuvant alleviating side effects in lithium-treated subjects is worth being continued.”

“Thus, at 72 hr, 48 hr following the removal of selenium, Ca++ had increased to a concentration of 0.7 mM. Ca++ accumulation appears to be a consequence of osmotic stress rather than pump inhibition while Na accumulation is a direct consequence of Se-inhibited Na pump.”

“Parameters indicative of pancreatic growth (tissue weight, DNA and protein contents, cellular protein concentrations) increased significantly after 2 days of CA or CA + SE and reached a plateau between days 4 and 10.”

“ Selenium retention increased quadratically as dietary Ca increased, whereas Ca retention was not affected by dietary Se.”