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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Selenium
supplement:
Broccoli Sprout Extract
Research Papers that Mention the Interaction
“Thus, selenium enrichment of broccoli has the potential to enhance the anticancer properties of broccoli sprouts.”
Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells“Supranutritional amounts of Se supplied as high Se broccoli significantly decreased (P: < 0.05) the incidence of aberrant crypts (AC) and aberrant crypt foci (ACF; preneoplastic lesions indicative of colon cancer) compared with other dietary treatments.”
Selenium from high selenium broccoli protects rats from colon cancer.“Although induction of TR1 mRNA by broccoli sprout extract (1.6-8μM) was only 1.7-2.2-fold, co-treatment with Se (0.2-1μM) enhanced the expression of TR1 mRNA (3.0-3.3-fold).”
“In this study, broccoli sprout extract (a rich source of the isothiocyanates sulforaphane and iberin) and Se interacted synergistically to induce TR1 in immortalised human hepatocytes.”
“Moreover, broccoli sprout extract induced the cellular concentration of TR1 and TR enzymatic activity, an induction that was augmented by Se addition.”
Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes.
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