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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Secretin and Serotonin



Research Papers that Mention the Interaction

It can suppress the secretion of serotonin , as well as the gastroenteropancreatic peptides gastrin, vasoactive intestinal peptide (VIP), insulin, glucagon, secretin , motilin, and pancreatic polypeptide.
Connecticut medicine  •  1989  |  View Paper
5-HT also mediates the action of secretin and CCK.
Pancreatology  •  2001  |  View Paper
The combined administration of serotonin and secretin inhibited gastric acid secretion to a greater magnitude than either secretagogue alone.
American journal of surgery  •  1985  |  View Paper
These findings suggest that secretin promotes the metabolism of serotonin and dopamine in the central nervous system, which may contribute to improvement in clinical symptoms of autism.
No to hattatsu = Brain and development  •  2004  |  View Paper
Under the stimulation with secretin, 5-HT decreased the intracellular pH (pH(i)) and reduced the rate of pH(i) recovery after acid loading with NH(4)(+), suggesting that 5-HT inhibits the intracellular accumulation of HCO3(-).
The Journal of clinical investigation  •  2001  |  View Paper
In a separate study, intraduodenal, but not intraileal, 5-HT application induced a dose-dependent increase in pancreatic protein secretion , which was not blocked by the CCK-A antagonist CR-1409.
American journal of physiology. Gastrointestinal and liver physiology  •  2001  |  View Paper
5-HT inhibits spontaneous fluid secretion as well as stimulated secretion with secretin (cAMP mediated) or ACh (Ca2+ mediated) in the isolated guinea pig pancreatic ducts.
Journal of Korean medical science  •  2000  |  View Paper