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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“It can suppress the secretion of serotonin , as well as the gastroenteropancreatic peptides gastrin, vasoactive intestinal peptide (VIP), insulin, glucagon, secretin , motilin, and pancreatic polypeptide.”
Debut of a somatostatin analog: octreotide in review.“ 5-HT also mediates the action of secretin and CCK.”
“The combined administration of serotonin and secretin inhibited gastric acid secretion to a greater magnitude than either secretagogue alone.”
“These findings suggest that secretin promotes the metabolism of serotonin and dopamine in the central nervous system, which may contribute to improvement in clinical symptoms of autism.”
“Under the stimulation with secretin, 5-HT decreased the intracellular pH (pH(i)) and reduced the rate of pH(i) recovery after acid loading with NH(4)(+), suggesting that 5-HT inhibits the intracellular accumulation of HCO3(-).”
5-hydroxytryptamine strongly inhibits fluid secretion in guinea pig pancreatic duct cells.“In a separate study, intraduodenal, but not intraileal, 5-HT application induced a dose-dependent increase in pancreatic protein secretion , which was not blocked by the CCK-A antagonist CR-1409.”
“ 5-HT inhibits spontaneous fluid secretion as well as stimulated secretion with secretin (cAMP mediated) or ACh (Ca2+ mediated) in the isolated guinea pig pancreatic ducts.”
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