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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Secretin
drug:
Chenodeoxycholate
Research Papers that Mention the Interaction
“In vitro treatment of CDCA or fexaramine elevated the SHP transcript level and occupancy on secretin promoter.”
Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP).“On the other hand, chenodeoxycholic acid exerts the strongest stimulating effect on secretin release, which may account for the stimulating effect of this bile acid on exocrine pancreatic secretion.”
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