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“In primary cultures, secretin caused a dose-dependent increase in intracellular adenosine 3',5'-cyclic monophosphate (cAMP) and stimulated electrogenic transepithelial ion transport.”
The American journal of physiology • 1997 | View Paper
“Consistent with these findings, secretin increased intracellular levels of adenosine 3',5'-cyclic monophosphate (cAMP) and 36Cl- efflux rates in medium and large cholangiocytes but not in small cholangiocytes.”
The American journal of physiology • 1997 | View Paper
“ Secretin (5 × 10−9-5 × 10−7M) increased enzyme secretion as well as cellular adenosine 3',5'-cyclic monophosphate (cyclic AMP) in a concentration- dependent manner in dispersed rat pancreatic acini.”
“In the absence of theophylline, secretin increased the level of cAMP in a dose-dependent manner with a maximum at 10(-6) M. With supramaximal doses the concentration of cAMP decreased.”
“In the absence of theophylline, secretin increased the level of cAMP in a dose-dependent manner with a maximum at 10(-6) M. With supramaximal doses the concentration of cAMP decreased.”