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Last Updated: a year ago

Possible Interaction: Scopolamine and Oxiracetam

supplement:

Oxiracetam

Research Papers that Mention the Interaction

The effect of the SC injection of 0.2 mg/kg scopolamine on the efficiency of responding was antagonized by the IP administration of 30 mg/kg oxiracetam , while the effect on running time induced by the same dose of scopolamine was not.
Psychopharmacology  •  2007  |  View Paper
By contrast, oxiracetam attenuated the effect of scopolamine in the hippocampus, frontal cortex and striatum but not in the amygdala.
Psychopharmacology  •  2005  |  View Paper
Experiment 2: Oxiracetam administered at doses of 3, 10 and 30 mg/kg immediately after the acquisition session prevented the scopolamine induced prolongation of the transfer latency.
Behavioural Brain Research  •  2002  |  View Paper
Scopolamine also prevented the increase of particulate PKC elicited by oxiracetam in vitro.
Life sciences  •  1993  |  View Paper
Interactive effects in the learning situation, but not in a test of general activity, were also found when oxiracetam was combined with the anticholinergic agent scopolamine.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  1989  |  View Paper
Oxiracetam , aniracetam and pyroglutamic acid prevent brain acetylcholine decrease and amnesia induced by scopolamine.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  1989  |  View Paper
Oxiracetam (50 and 100 mg/kg IP) administered 30 min before scopolamine reduced the scopolamine-induced amnesic effect and decrease in acetylcholine level in the cortex and hippocampus, but not in the striatum.
Pharmacology Biochemistry and Behavior  •  1987  |  View Paper