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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Salicylic Acid
supplement:
Arachidonate
Research Papers that Mention the Interaction
“ Salicylate at concentrations above 5 mM effectively blocked the inhibition of cyclo-oxygenase activity and platelet aggregation in response to arachidonate.”
Effect of acetaminophen and salicylate on aspirin-induced inhibition of human platelet cyclo-oxygenase.“ Salicylate also increased the arachidonate content of the whole cochlea in vivo.”
“These results suggest that salicylate inhibits cochlear cyclooxygenase, which increased levels of arachidonate.”
Salicylate Enables Cochlear Arachidonic-Acid-Sensitive NMDA Receptor Responses“Local application of sodium arachidonate decreased the activity in 17 of 28 warm-units and excited 12 of 16 cold-units, and the effects of arachidonate were blocked by sodium salicylate.”
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