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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Saccharin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Comparison of the sequence of Tas1r3 with … found 1) an inverse correlation between calcium … saccharin preference scores across primarily domesticus strains, which was associated with an I60T substitution in T1R3, and 2) … unique to the PWK strain and thus may be responsible for its strong calcium and magnesium preference.”
Involvement of T1R3 in calcium-magnesium taste.“Simple cyclic sulfonamides, like saccharin (SAC), have shown up to a 60-fold selectivity towards CA IX over other ubiquitous CA isoforms, with greater selectivity obtained applying the "tail-approach" to derivatize SAC with a methylene triazole linker that connected to a "tail" beta glucoside.”
Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclization/deprotection strategy.“Previously, saccharin , a commonly used artificial sweetener, has been observed to selectively inhibit CA IX over other CA isoforms.”
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