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“Taken together, the results of our studies indicate that the cholesterol-lowering effects of garlic extract , such as AGE, stem in part from inhibition of hepatic cholesterol synthesis by water-soluble sulfur compounds, especially SAC.”
“These data demonstrate that garlic extract and SAC , due to their antioxidant activity, differentially regulate NO production by inhibiting iNOS expression in macrophages while increasing NO in endothelial cells.”
“These additional biological effects attributed to AGE may be due to compounds, such as S-allylcysteine , S-allylmercaptocysteine, N(alpha)-fructosyl arginine and others, formed during the extraction process.”
“The protection offered by aged garlic may be attributed to SAC.”
“When compared with other groups, the combined therapy of high doses of AGE and SAC given alone or together with CAR caused a significant decrease in serum LDH and CK-MB activities.”
Indian journal of pharmacology • 2014 | View Paper
“The organosulfur compounds, S-allyl-L-cysteine and S-allylmercapto-L-cysteine, are responsible, at least in part, for the antioxidant activity of AGE.”