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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: S-Adenosylmethionine and Serine

supplement:

Serine

Research Papers that Mention the Interaction

S-adenosylmethionine affects serine methylation and activates serine-dependent de novo ATP synthesis.
Cell biochemistry and biophysics  •  2020  |  View Paper
L-serine increased glutathione and S-adenosylmethionine by 94.0% and 30.6%, respectively, compared with the ethanol group.
The Journal of nutrition  •  2015  |  View Paper
When hepatocytes from ethanol‐fed rats supplemented with SAM were incubated with methionine plus serine or N‐acetylcysteine, mitochondrial glutathione increased in parallel with cytosol, an effect not observed in cells from ethanol‐fed rats without SAM.
Hepatology  •  1995  |  View Paper
Notably, serine had a role in regulating S-adenosylmethionine (SAM) to facilitate kidney organoid formation by altering DNA methylation.
Frontiers in Genetics  •  2021  |  View Paper