supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
S-Adenosylmethionine
supplement:
Selenium
Research Papers that Mention the Interaction
“At low concentration, Se can decrease As toxicity via excretion of As-Se compound [(GS3)2AsSe](-), but at high concentration, excessive Se can enhance As toxicity by reacting with S-adenosylmethionine and glutathione, and modifying the structure and activity of arsenite methyltransferase.”
Arsenic and selenium toxicity and their interactive effects in humans.“ S-adenosylmethionine was increased in HT29 cells at cytotoxic doses of selenium (1.0 to 6.0 ppm).”
“The elevation of SAM resulting from the subchronic administration of selenium may be one mechanism involved in the well-known chemopreventive effects in experimental models.”
Increased levels of S-adenosylmethionine in the livers of rats fed various forms of selenium.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback