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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
S-Adenosylmethionine
drug:
Pemetrexed
Research Papers that Mention the Interaction
“Reduced MTA (5'-deoxy-5'-methylthioadenosine)-degrading activity may compensate for the deficient production of the precursor S-adenosylmethionine , allowing maintenance of intracellular MTA levels that may be critical to ensure cellular adaptation to physiopathological conditions such as inflammation.”
Redox regulation of methylthioadenosine phosphorylase in liver cells: molecular mechanism and functional implications.“This chapter reviews recent evidence that points to an important role for MTA as an intermediary in the beneficial pharmaceutical action of orally ingested S-adenosyl-l-methionine (AdoMet, SAMe).”
16 Inhibition of mammalian protein methyltransferases by 5'-methylthioadenosine (MTA): A mechanism of action of dietary same?
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