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Last Updated: 2 years ago

Possible Interaction: Rutin and Vitamin E

supplement:

Rutin

supplement:

Vitamin E

Research Papers that Mention the Interaction

Rutin reduced UV-induced proinflammatory response and ROS generation and enhanced the activity/levels of antioxidants (SOD, GSH-Px, vitamin E , GSH, and Trx).
Oxidative medicine and cellular longevity  •  2017  |  View Paper
Although, rutin (R) in combination with vitamin E (VE) has been shown to synergistically inhibit oxidative damage, it is unclear whether the combination of R and VE (R+VE) inhibits VEGF secretion in tumor cells.
Chemico-biological interactions  •  2010  |  View Paper
When these compounds are used in combination, an additive effect is observed with alpha-tocopherol and ascorbic acid or rutin , while a supra-additive effect (synergism) is noted with ascorbic acid and rutin.
Pharmacology  •  1991  |  View Paper
Data confirmed that RH improves spatial memory function by increasing acetylcholine availability, boosting endogenous antioxidant potential, activating cell survival and inhibiting apoptotic pathways, an effect that is more effective when RH was conjugated with α-tocopherol.
In conclusion, RH affords a potent neuroprotection against CdCl2-induced brain damage and memory dysfunction and co-administration of α-tocopherol enhances its activity.
Archives of physiology and biochemistry  •  2018  |  View Paper