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Last Updated: 2 years ago

Possible Interaction: Rutin and Ng-Nitroarginine Methyl Ester

Research Papers that Mention the Interaction

However, l-NAME (5 mg/kg) pre-treatment with rutin (40 mg/kg) potentiated their protective effect which was significant as compared to their effect per se.
Pharmacological reports : PR  •  2014  |  View Paper
Furthermore, pretreatment of N(G)-nitro-L-arginine methyl ester (10 mg/kg, intraperitoneally), a nonspecific nitric oxide synthase inhibitor, with subeffective dose of rutin (40 mg/kg) potentiated the protective effects; however, pretreatment of L-arginine (100 mg/kg; intraperitoneally), an NO donor, reversed the effects of rutin.
The Journal of surgical research  •  2014  |  View Paper
Administration of L-NAME prior to administration of quercetin and rutin, significantly reduced the cerebroprotection offered by quercetin and rutin.
European review for medical and pharmacological sciences  •  2013  |  View Paper
Inhibited the endothelial nitric oxide synthase (eNOS) by NG-Nitro-L-arginine Methyl Ester L-NAME ) or removed the PA endothelium would decrease the relaxation effect of rutin.
International angiology : a journal of the International Union of Angiology  •  2012  |  View Paper
L-NAME abolished the cardioprotective actions of rutin more strongly than the cardioprotective actions of quercetin.
Indian journal of experimental biology  •  2011  |  View Paper
Pretreatment with L-NAME (0.1 mmol/L) abolished the vasorelaxation by rutin ,but did not influence the vasodilating effect of quercetin in endothelium-intact rings.
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences  •  2006  |  View Paper
Pretreatment with L-NAME (0.1 mmol/L), methylene blue (10 mumol/L), glibenclamide (10 mmol/L) or indomethacin (10 mmol/L) attenuated the vasorelaxation induced by rutin in endothelium-intact rings.
2005 IEEE Engineering in Medicine and Biology 27th Annual Conference  •  2005  |  View Paper