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Last Updated: 2 years ago

Possible Interaction: Rutin and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

Manuscript reports a number of constituents with evident potential in prevention of DOX cardiotoxicity e.g. proanthocyanidins, epigallocatechin-3-gallate, S-allylcysteine, reseveratrol, rutoside etc.
Current clinical pharmacology  •  2014  |  View Paper
These authors claimed that rutin protects against doxorubicin cardiotoxicity through suppression of autophagy and apoptosis [8].
Biochimica et biophysica acta. Molecular basis of disease  •  2017  |  View Paper
We had previously identified that rutin inhibits doxorubicin (Dox-) -induced cognitive decline in healthy rats.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer  •  2019  |  View Paper
Collectively, our findings suggest that suppression of autophagy and apoptosis by administration of rutin could attenuate doxorubicin-induced cardiotoxicity, which enhances our knowledge to explore new drugs and strategies for combating this devastating side effect induced by doxorubicin.
Biochimica et biophysica acta. Molecular basis of disease  •  2017  |  View Paper