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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Rolipram and Yohimbine

supplement:

Yohimbine

Research Papers that Mention the Interaction

For example, the selective type III phosphodiesterase inhibitor rolipram has been shown to antagonize reserpine-induced hypothermia and also to potentiate yohimbine lethality, two tests that are indicative of antidepressant activity.
Journal of medicinal chemistry  •  1985  |  View Paper
When both rolipram and Ro-20-1724 were tested after phentolamine (1 µM) or yohimbine (0.1 µM), they were significantly (P<0.01) less effective.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  1998  |  View Paper