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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“For example, the selective type III phosphodiesterase inhibitor rolipram has been shown to antagonize reserpine-induced hypothermia and also to potentiate yohimbine lethality, two tests that are indicative of antidepressant activity.”
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.“When both rolipram and Ro-20-1724 were tested after phentolamine (1 µM) or yohimbine (0.1 µM), they were significantly (P<0.01) less effective.”
Effect of selective phosphodiesterase inhibitors on synaptic transmission in the guinea-pig ileum
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