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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Rolipram
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“ Rolipram (100 μM), denbufylline (100 μM) and BRL 61063 (100 μM) stimulated the release of corticotrophin (ir‐ACTH) from pituitary tissue in vitro (P<0.05) but in lower concentrations they were without significant effect.”
Stimulation of the hypothalamo‐pituitary‐adrenal axis in the rat by three selective type‐4 phosphodiesterase inhibitors: in vitro and in vivo studies“Both IBMX and Rolipram enhanced the AVP-stimulated secretion of ACTH in cultured anterior pituitary cells, but not in AtT-20 corticotrophs which lack functional AVP receptors.”
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