supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Rituximab
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“We reported that rituximab induced the colocalization of both the Orai1 Ca2+ release-activated Ca2+ channel ( CRAC ) and the endoplasmic reticulum Ca2+ sensor stromal interaction molecule 1 with CD20 and CD95 into a cluster, eliciting a polarized store-operated Ca2+ entry (SOCE).”
Localized Store-Operated Calcium Influx Represses CD95-Dependent Apoptotic Effects of Rituximab in Non-Hodgkin B Lymphomas“In this report, we demonstrate that monomeric rituximab , at the high concentrations found in plasma following infusion of therapeutic doses, induces prolonged low-amplitude release of calcium from thapsigargin-sensitive intracellular stores and reduces the growth of Ramos B cells in culture.”
“Recently, several and severe viral infections have been reported after the use of rituximab (Rituxan; IDEC Pharmaceuticals, San Diego, CA , USA/Genentech, South San Francisco, CA, USA) (3, 4).”
Monoclonal antibodies and cytomegalovirus infections
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback