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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ritonavir
supplement:
St John's Wort
Research Papers that Mention the Interaction
“In vitro studies from our laboratory suggest that short-term exposure with pure herbal agents such as hypericin, kaempferol and quercetin or extract of SJW resulted in higher uptake or influx of ritonavir and erythromycin.”
“Results from clinical studies and case reports indicate that self-administered SJW reduce steady state plasma concentrations of amitriptyline, cyclosporine, digoxin, fexofenadine, amprenavir, indonavir, lopinavir, ritonavir , saquinavir, benzodiazepines, theophyline, irinotecan, midazolan and warfarin.”
MDR- and CYP3A4-mediated drug-herbal interactions.
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