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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Riluzole
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“In addition, pretreatment with nifedipine or riluzole also significantly reduced cytosolic free calcium but did not affect cell injury, whereas tetrodotoxin had no affect on either outcome parameter.”
Dynamic mechanical deformation of neurons triggers an acute calcium response and cell injury involving the N‐methyl‐D‐aspartate glutamate receptor“ Riluzole also depressed the intrinsic burst generation of Pre-I neurons in low calcium and high magnesium solution.”
Effects of riluzole on respiratory rhythm generation in the brainstem-spinal cord preparation from newborn rat“In summary, riluzole blocked the persistent sodium current fully, and the calcium one partly, plus it decreased glutamatergic transmission probably via inhibition of PKC that regulated presynaptic NMDA receptors having a facilitatory effect on glutamate release.”
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