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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Rilmenidine
supplement:
Yohimbine
Research Papers that Mention the Interaction
“The hypotensive effects of rilmenidine are antagonised by idazoxan and yohimbine , but idazoxan (imidazoline structure) is six times more potent than yohimbine (a selective alpha 2-antagonist).”
Distinctive features of rilmenidine possibly related to its selectivity for imidazoline receptors.“Similarly, clonidine and rilmenidine in the same dose range reduced the oedema formation induced by carrageenan, yohimbine and the α2A-adrenoceptor antagonist BRL-44408 (3 μmol/kg i.p.)”
Pharmacological analysis of α2-adrenoceptor subtypes mediating analgesic, anti-inflammatory and gastroprotective actions“ Yohimbine (a selective alpha 2-adrenoceptor antagonist) antagonized the inhibitory concentration effect curve to rilmenidine in a competitive manner.”
“The effects of rilmenidine , moxonidine, and UK 14304 were antagonized by intravenously administered yohimbine , SK&F86466, and RX821002.”
“ Yohimbine 0.1 and 0.5 mg kg-1, when injected subsequently, attenuated and at the higher dose abolished all effects of rilmenidine.”
“2 Pretreatment with the same dose of yohimbine or idazoxan shifted the rilmenidine dose‐response curves for its hypotensive and bradycardic effects to the right.”
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