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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Rifampin
supplement:
Polypeptides
Research Papers that Mention the Interaction
“Recent studies have highlighted the potential use of rifampicin as an inhibitor of amyloid formation by a variety of polypeptides ; however, there are conflicting reports on its ability to inhibit amyloid formation by islet amyloid polypeptide (IAPP).”
Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death.“These data indicate that … of vaccinia either rifampicin binds … polypeptide in the manner conceived for bacterial RNA polymerase and prevents the formation of an initiation complex or that the inhibitor … the function of only one out of two or more RNA polymerases that may be induced by the virus.”
Biogenesis of vaccinia: effect of rifampicin on transcription.“ Rifampicin appears to act by interrupting earlier maturational events which precede the formation of the core polypeptide.”
“ Rifampicin completely prevented the formation of the core polypeptide without inhibiting the synthesis of the precursor.”
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