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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ribose
drug:
Pimagedine
Research Papers that Mention the Interaction
“Because these effects of d-ribose were counteracted by aminoguanidine or N-acetylcysteine, reactive oxygen species, generated by the glycation reaction, appears to be involved in the phenomena.¶Conclusion/interpretation.”
Induction of glycation suppresses glucokinase gene expression in HIT-T15 cells“These effects of D-ribose seemed almost irreversible but could be prevented by addition of 1 mM aminoguanidine or 10 mM N-acetylcysteine, thus suggesting that glycation and reactive oxygen species, generated through the glycation reaction, serve as mediators of the phenomena.”
“Replacing glucose with ribose showed a quicker increase in cross-linking and less effect on cross-linking by adding aminoguanidine , demonstrating the higher reactivity of pentoses above hexoses.”
Glucose-mediated cross-linking of collagen in rat tendon and skin.
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