“Our study demonstrated that D-ribose induced AGE accumulation and ROS production in mesangial cell and caused mitochondrial apoptosis, but kaempferol could attenuate these changes and its protective effect might be related to the repair of autophagy.”
“Subsequently, it was confirmed that kaempferol repaired the autophagy disturbance induced by D-ribose , and 3-MA could reverse the protective effect of kaempferol under D-ribose condition.”