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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ribose and Gemcitabine

supplement:

Ribose

Research Papers that Mention the Interaction

Our structures reveal that GemdP binds differently from its analogue, cytidine diphosphate; because of unusual interactions of the geminal fluorines, the ribose and base of GemdP shift substantially, and loop 2, which mediates substrate specificity, adopts different conformations when binding to GemdP and cytidine diphosphate.
Proceedings of the National Academy of Sciences of the United States of America  •  2006  |  View Paper