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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Ribose
drug:
Gemcitabine
Research Papers that Mention the Interaction
“Our structures reveal that GemdP binds differently from its analogue, cytidine diphosphate; because of unusual interactions of the geminal fluorines, the ribose and base of GemdP shift substantially, and loop 2, which mediates substrate specificity, adopts different conformations when binding to GemdP and cytidine diphosphate.”
Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.
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