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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Riboflavin
supplement:
Polypeptides
Research Papers that Mention the Interaction
“This study indicates for the first time a profound involvement of riboflavin/flavin cofactors in modulating the level of a number of functionally coordinated polypeptides involved in fatty acyl‐CoA and amino acid metabolism, extending the number of enzymatic pathways altered in riboflavin‐responsive multiple acyl‐CoA dehydrogenase deficiency.”
Coordinated and reversible reduction of enzymes involved in terminal oxidative metabolism in skeletal muscle mitochondria from a riboflavin‐responsive, multiple acyl‐CoA dehydrogenase deficiency patient“These observations demonstrate that FMN binds rapidly to the unfolded polypeptide and guides folding straight to the native state.”
Folding of Desulfovibrio desulfuricans flavodoxin is accelerated by cofactor fly-casting.“Furthermore, the FT-IR difference spectra reveal that the redox transitions of the FMN and of the FeS clusters induce strong reorganizations of the polypeptide backbone.”
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