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“It is proposed that photoexcited riboflavin can perform a one-electron oxidation of ascorbate generating a riboflavin radical.”
“ Riboflavin in the presence of light stimulates the formation of ESR-detectable ascorbyl semiquinone radicals and stimulates O2 consumption (oxidation) by ascorbate in a manner dependent upon the concentration of riboflavin.”
“This 'pro-oxidant' activation of ascorbate by riboflavin is discussed in the context of previous studies on riboflavin phototoxicology.”
“FMN antagonists and Fe*-complexing agents (5, 9), serotonin, reduced glutathione, ascorbate , diethylstilbestrol, cytochrome c, and anaerobiosis (7) inhibited the activity of the FMN + Fe* or of the FMN-supplemented preparations.”