supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Retinyl Palmitate
Research Papers that Mention the Interaction
“Both … DOX significantly (p<0.05) increased with the index and frequency of damages, clastogenic and/or aneugenic effects with the augmenting of micronuclei, demonstrating … cytotoxicity interference on the ratio of normochromatic to polychromatic erythrocytes and bone marrow cells of mice, that were found to reduce in RP treatment ….”
Cytogenotoxicological defense of retinyl palmitate in the front damage of antineoplastics.“Pretreatment of rats with two daily subcutaneous injections of retinol palmitate (0.25 g/kg body wt), for 2 days, before injecting doxorubicin , inhibited peroxidation of heart and brain membrane lipids.”
“However RP failed to potentiate the antitumor effects of adriamycin (ADM) and 6-mercaptopurine (6-MP) against sarcoma 180.”
“…,RP (167 mg/kg, or 333 mg/kg) enhanced the antitumor effects … 50 mg/kg), MTX (1 mg/kg, or 2 mg/kg), ADM (0.2 mg/kg), ACNU (5 mg/kg) and cis-dichlorodiammine-platinum (CDDP) (… extent, but it did not potentiate the antitumor effect of 5-FU.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback