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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Retinaldehyde
supplement:
Vitamin A
Research Papers that Mention the Interaction
“All-trans retinol was a potent inhibitor of ALDH1 activity, and inhibited all-trans retinal oxidation uncompetitively.”
Kinetic properties of the human liver cytosolic aldehyde dehydrogenase for retinal isomers.“RESULTS Supplementation of vi amin A at 26 or 52 mg significantly modulated the expression of ret inal genes in the O but not in the L phenotype.”
Vitamin A supplementation ameliorates obesity-associated retinal degeneration in WNIN/Ob rats.“The effectiveness of this process is considerably inhibited in the presence of all-trans retinol , confirming previous data in model membranes.”
“All-trans retinoic … (t-RA) and all-trans retinol significantly inhibited a LPS-induced PGE(2) production as assessed by enzyme-linked immunosorbant assay (ELISA) and COX-2 protein expression as assessed by Western blot assay in mouse peritoneal macrophages, after knocking out the COX-1 activity by aspirin.”
“Addition of 5 or 10 micro molar all-trans retinol stimulated a mild increase in reporter activity, however, the increase was not statistically significant.”
“As compared to vehicle‐treated controls, RAL‐treated mouse skin contained low amounts of all‐trans RA and 13‐cis‐RA, whereas ROL content increased 10‐fold and retinyl esters 30‐fold after RAL application.”
“Furthermore, all-trans retinol inhibited CSC-induced basal cell proliferation.”
“Furthermore, all-trans retinol inhibited CSC-induced basal cell proliferation.”
“ All-trans retinol supplementation (6 μM) to the maturation medium at 5% O2 levels significantly increased blastocyst yield and total cell number (P < 0.05).”
Effect of vitamin A supplementation at different gaseous environments on in vitro development of pre-implantation sheep embryos to the blastocyst stage.“Addition of 5 μM all-trans retinol resulted in significant increase in blastocyst rate and total cell number (P < 0.001) when compared with control.”
“Supplementation of 10 μM all-trans retinol under 5% O2, significantly reduced blastocyst formation and cell numbers.”
“Supplementation of 5 μM all-trans retinol significantly reduced the comet tail (P < 0.001) when compared with control.”
“Treatment with 5 μM all-trans retinol improved the blastocyst formation (P < 0.001) when compared with control and significant increase (P < 0.01) in total cell number was observed in 5 μM group when compared with control.”
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