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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Resveratrol
drug:
Pemetrexed
Research Papers that Mention the Interaction
“Importantly, pharmacological dietary agents, namely resveratrol and its analogs, are potentially applicable to prostate cancer prevention, treatment, and control of cancer progression due to their potent inhibitory effects on MTA proteins.”
MTA family of proteins in prostate cancer: biology, significance, and therapeutic opportunities“Combining resveratrol with pemetrexed resulted in a synergistic cytotoxic effect, accompanied with the reduction of phospho-p38 MAPK and ERCC1 protein levels, and a DNA repair capacity.”
“In this study, for the first time, we … demonstrated the synergistic effect of combined treatment with resveratrol and pemetrexed in human NSCLC cells through downregulation of the MKK3/6-p38 MAPK-ERCC1 signal, suggesting a potential benefit of combining resveratrol and pemetrexed to treat lung cancer in the future.”
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