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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Resveratrol
drug:
Ici 182780
Research Papers that Mention the Interaction
“These effects of E2 on resveratrol action were blocked by ICI 182,780 ( ICI ), an inhibitor of the nuclear oestrogen receptor-α (ER).”
Oestrogen inhibits resveratrol-induced post-translational modification of p53 and apoptosis in breast cancer cells“Also, the effects of resveratrol could not be attenuated by ICI-182780 , a high affinity estrogen receptor antagonist.”
Resveratrol prevents RANKL-induced osteoclast differentiation of murine osteoclast progenitor RAW 264.7 cells through inhibition of ROS production.“ RES , in conjunction with ICI 182,780 ( ICI ), caused a down-regulation of both p53 and ERα as compared to the control.”
The regulation of tumor suppressor protein, p53, and estrogen receptor (ERα) by resveratrol in breast cancer cells
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