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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Resveratrol and Gefitinib

supplement:

Resveratrol

Research Papers that Mention the Interaction

Notably, 50 micromolar resveratrol and quercetin fully suppressed the low constitutive levels of type I interferon signaling and prevented its activation by the anti-EGFR cetuximab or gefitinib in cultured keratinocytes.
International journal of molecular sciences  •  2018  |  View Paper
The underlying mechanisms of synergism were investigated, and the results showed that cotreatment with Gef and Res could inhibit EGFR phosphorylation by increasing intracellular Gef accumulation through the impairment of Gef elimination from PC9/G cells.
This study demonstrated that resveratrol (Res) could synergize with Gef to inhibit the proliferation of Gef-resistant NSCLC cells.
Scientific reports  •  2015  |  View Paper