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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Resveratrol
drug:
Becaplermin
Research Papers that Mention the Interaction
“Conclusions These results indicate that resveratrol is an effective inhibitor of PDGF-BB-induced RPE cell migration via PDGFRβ, PI3K/Akt and MAPK pathways, but has no effects on the RPE cell adhesion to fibronectin.”
“In this study, we investigated the inhibitory effects of resveratrol on RPE cell migration induced by PDGF-BB , an isoform of PDGF, and adhesion to fibronectin, a major ECM component of PVR tissue.”
“Inhibitory effects of resveratrol on PDGF-BB-induced platelet-derived growth factor receptor β (PDGFRβ) and tyrosine phosphorylation and the underlying pathways of PI3K/Akt, ERK and p38 activation were found; however, resveratrol and PDGF-BB showed no effects on PDGFRα and JNK activation.”
Inhibitory Effects of Resveratrol on PDGF-BB-Induced Retinal Pigment Epithelial Cell Migration via PDGFRβ, PI3K/Akt and MAPK pathways“ RESV suppressed proliferation, migration and fibronectin synthesis induced by platelet-derived growth factor-BB or TGF-β2.”
Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy
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