“OBJECTIVE To observe the effect of the Soybean Isoflavaones on the mRNA expression … Osteoprotegerin (OPG), Osteoclast Differentiation Factor (ODF) and Macrophage Colony stimulating Factor M-CSF ) in bone tissue of ovariectomized rat, and to investigate the possible molecule mechanism of Soybean Isoflavaones antagonizing bone lose induced by postmenopausal osteoporosis.”